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Collagen-derived biomarkers reveal distinct fibrotic responses among cancer-associated fibroblasts | Scientific Reports

After treating dermal fibroblasts with iPSC-derived MVs, the expressions of collagens Iα1 and III transcripts (as the main fibrous extracellular matrix (ECM) proteins) were upregulated

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Linear regression analysis showed that a greater than 30–35% increase in serum IGF-I was needed to reduce visceral fat mass